IPO Arc: the rise and fall after listingIPO Arc

COAG

Lock-up windowHealthcare

Hemab Therapeutics Holdings, Inc. · NASDAQ Global Select · priced May 1, 2026 · $302M raised · Over $250M

Offer price
$18.00
Day 1
+88.9%
close vs offer
Peak
+205.2%
trading day 73
Now vs offer
+124.6%
$40.42 on Oct 29, 2026
Off peak
-48.4%
peak to subsequent low
Lock-up expiry
Oct 28, 2026
2d ago · from prospectus

Price since listing

  • Hype
  • Distribution
  • Lock-up window
  • Valley
  • Accumulation
  • Recovery

Volume bars are coloured by lifecycle phase. Markers: lock-up and early release (orange), earnings releases (E), follow-on offerings (F), research signals (rule id and signal; arrow up = buy signal, arrow down = sell or short signal, or sell signal for deals under $50M). Current phase: Lock-up window.

Performance since the IPO

  • COAG
  • S&P 500 (SPY)
  • Typical IPO over $250m
  • Middle 50% of those IPOs

COAG measured from its offer price; S&P 500 from the first trading day. The typical-IPO line is the median of 340 over $250m IPOs from 2014–2025, by trading day.

Company

Hemab Therapeutics Holdings, Inc. operates as a clinical-stage biotechnology company developing therapies that reimagine the treatment of blood coagulation disorders to sustain life and human resilience in United States of America and Denmark. Its products includes (HMB-001), is a bispecific antibody currently in Phase 1/2 clinical development for the prophylactic treatment of Glanzmann thrombasthenia and Phase 2 cli…

Sector
Healthcare
Industry
Biotechnology
Country
United States
Employees
59
Market cap
$1.8B

From the prospectus

Lock-up
180 days
Early release on earnings
No
Price-based early release
No
Staggered release
No
Float sold in IPO
38%
Locked shares per share sold
1.6×
Backed by
Venture capital
Lead underwriters
Goldman Sachs & Co. LLC, Jefferies LLC, Evercore Group L.L.C.
Dual-class shares
No
Controlled company
No
Foreign private issuer
No

Extracted from the final prospectus on SEC EDGAR.

Returns vs offer, compared with 135 IPOs over $250m

HorizonCOAGPeer medianPeers below offer
Day 1+88.9%+12.8%24% n=135
Day 20+58.3%+11.6%30% n=133
Day 60+162.6%+6.3%47% n=129
Day 120+96.3%-4.6%54% n=106
Day 180—-4.1%52% n=89

Research signals

  • BuyRule T1: buy signal for 60 sessions
    Sep 30, 2026 · Pre-unlock quality
    Past signals (642, deals of $50M and over): rose 47% · median -2.6% · dropped 25%+ during the hold 35%
    backtest

    Buy signals passed on returns relative to IPOs of the same year, size and age, most of which fall after listing. A buy signal can beat its peers and still lose money.

  • Sell or shortRule R20: sell or short signal for 100 sessions
    May 29, 2026 · Day-20 risk tier
    Past signals (118, deals of $50M and over): fell 70% · median -24.6% · rallied 25%+ during the hold 55%
    backtest

    Short-selling risk: losses on a short position have no limit and can exceed the amount put up; brokers can demand more margin, recall borrowed shares or close the position; borrow fees and any dividends are owed while short and are not in the figures shown; recent IPOs are often hard to borrow and prone to squeezes.

Rules frozen as v1; signals dated from Oct 29, 2026 are live, earlier ones show what the frozen rules would have flagged. See methodology.

The rules run independently, so one IPO can carry buy and sell signals at the same time; each label reports only its own rule's history.

Past figures cover all 4,312 signals the published frozen v1 rules produce on 2014–2025 IPOs, close to close over each signal's holding period. Returns start at the close of the signal session; signals are published after that close, so the first price available to a reader is the next session's. Only 1,192 of 2,368 operating-company IPOs from those years have usable Yahoo Finance price data; most of the rest no longer trade under their IPO ticker (delisted, acquired or renamed), so the figures probably understate declines. These are hypothetical results, not trades: the rules were selected on these same years with the benefit of hindsight, so the figures likely overstate what live signals will do. The live track record is the real test. Trading costs and borrow fees are not included. Past results do not predict future results.

Research signals only, not investment advice. Lock-up terms come from prospectuses; prices from Yahoo Finance and may be delayed or wrong.